Can Flu Vaccine Improve COVID Danger?

For years, issues have been raised that earlier flu vaccination appears to extend sufferers’ danger of contracting extra extreme pandemic sickness. This occurred through the 2008 to 2009 flu season, when prior vaccination with the seasonal flu vaccine was related to an elevated danger of H1N1 “swine flu” throughout spring/summer season 2009 in Canada.1

A January 2020 research printed within the journal Vaccine additionally discovered folks have been extra more likely to get some type of coronavirus an infection if that they had been vaccinated towards influenza through the 2017 to 2018 flu season.2

In comparison with unvaccinated people, those that had acquired a seasonal flu shot have been 36% extra more likely to contract unspecified coronavirus an infection (it didn’t particularly point out SARS-CoV-2, the coronavirus that causes COVID-19) and 51% extra more likely to contract human metapneumovirus (hMPV) an infection, which has signs much like COVID-19.3

Once more, in October 2020, one other constructive affiliation was discovered between COVID-19 deaths and flu vaccination charges within the aged,4 elevating additional questions concerning the doubtlessly severe unintended negative effects of annual flu pictures.

Flu Vaccination Linked to Elevated Danger of COVID-19 Loss of life

Christian Wehenkel, a professor of forest genetics, forest ecosystem evaluation, forestry, biometrics, forest development and biodiversity with the Universidad Juarez del Estado de Durango, and a PeerJ editor, analyzed information units from 39 nations with greater than one-half million inhabitants.5 He anticipated to search out that prior flu vaccination can be linked to decrease COVID-19 dying danger, however as a substitute the info revealed the other.

Amongst folks aged 65 years and older, flu vaccination was positively related to COVID-19 deaths, that means those that acquired a flu vaccine have been extra more likely to die from COVID-19. “Opposite to expectations, the current worldwide evaluation and European sub-analysis don’t help the beforehand reported damaging affiliation between COVID-19 deaths (DPMI) and IVR [influenza vaccination rate] in aged folks,” Wehenkel wrote.

A Might 2020 evaluation by on-line information publication The Gateway Pundit equally discovered that European nations with the very best COVID-19 dying charges had excessive charges of flu vaccination — at the very least 50% —  among the many aged.6 For example, they wrote, “Denmark and Germany, with decrease use of the flu vaccine, had significantly decrease Covid-19 mortality.”

They tried to replace their figures for fall 2020, and have been capable of replace COVID-19 mortality charges however didn’t get hold of present vaccination information. Spikes in COVID-19 deaths have been famous, which they advised might be associated to a sudden uptick in flu vaccination in nations that had beforehand decrease vaccination charges:7

“This [increase in COVID-19 deaths] may merely be as a result of virus reaching endemic degree later in east Europe, however one other issue might be sudden enhance in flu vaccination in counties of hitherto low uptake. Are they unwittingly endangering their seniors?

The World Well being Group is vigorously selling flu vaccination in Europe, with posters warning ‘don’t carry dwelling an undesirable customer: defend your loved ones by getting vaccinated.’ The Covid-19 pandemic has terrified the general public and many individuals see a vaccine as the one technique of escape.”

Wehenkel’s information, nonetheless, picks up the place they left off, displaying by scatterplot a transparent affiliation of COVID-19 deaths per million inhabitants with flu vaccination price, as much as July 25, 2020 (every dot represents a unique European nation):8,9

COVID-19 deaths per million inhabitants

The Downside With Pathogenic Priming

Given the PeerJ research’s extremely controversial discovering, which, if confirmed to be causative, would name into query annual flu vaccination, a writer’s word on the high reminds readers that correlation doesn’t essentially imply causation.

“[T]his article shouldn’t be taken to recommend that receiving the influenza vaccination leads to an elevated danger of dying for a person with COVID-19 as there could also be many confounding elements at play (together with, for instance, socioeconomic elements),” it reads.10 It additionally doesn’t rule out causation, nonetheless, and it is a potential hyperlink that have to be urgently explored. The Gateway Pundit defined:11

“It’s proper to ask the query: are sufferers who die of / with Covid-19 extra more likely to have acquired the flu vaccine? Given the clear correlation from Wehenkel’s information, an pressing investigation is required to establish whether or not the big enhance in Covid-19 deaths in japanese Europe within the autumn of 2020 correlates with a rise in flu jabs in autumn 2020 in those self same nations.”

They didn’t cease there:12

“This leads on to the additional explosive query: are flu jabs not solely correlative with Covid-19 mortality, however causative by means of pathogenic priming? If the info from autumn 2020 affirm correlation, causation must be investigated with rigor and urgency.”

What’s pathogenic priming? It’s a situation wherein, reasonably than enhancing your immunity towards the an infection, publicity to a virus or vaccine enhances the virus’ skill to enter and infect your cells, leading to extra extreme illness.13

Analysis printed within the Journal of Translational Autoimmunity confirmed that remedy with a vaccine could enhance the dangers related to a wild sort virus reasonably than defend towards it, and concluded, as its title suggests, “Pathogenic priming seemingly contributes to severe and demanding sickness and mortality in COVID-19 by way of automimmunity.”14

Coronavirus Vaccines Have Enhanced Illness within the Previous

The Journal of Translational Autoimmunity article, written by James Lyons-Weiler with the Institute for Pure and Utilized Information, a nonprofit group that performs scientific analysis within the public curiosity, explains how pathogenic priming occurred throughout earlier trials of a SARS coronavirus vaccine:15

“In SARS, a sort of ‘priming’ of the immune system was noticed throughout animal research of SARS spike protein-based vaccines resulting in elevated morbidity and mortality in vaccinated animals who have been subsequently uncovered to wild SARS virus.

The issue, highlighted in two research, grew to become apparent following post-vaccination problem with the SARS virus … recombinant SARS spike-protein-based vaccines not solely failed to supply safety from SARS-CoV an infection, but in addition that the mice skilled elevated immunopathology with eosinophilic infiltrates of their lungs.

Equally … ferrets beforehand vaccinated towards SARS-CoV additionally developed a powerful inflammatory response in liver tissue (hepatitis). Each research suspected a ‘mobile immune response.’

Some of these unlucky outcomes are generally known as ‘immune enhancement’; nonetheless, this practically euphemistic phrase fails to convey the elevated danger of sickness and dying resulting from prior publicity to the SARS spike protein. For that reason, I seek advice from the idea as ‘pathogen priming’.”

On the time, even long-time pro-vaccine advocate Dr. Peter Hotez, dean of the Nationwide Faculty of Tropical Medication and professor of pediatrics and molecular virology and microbiology at Baylor School of Medication, was shaken. In response to a characteristic printed in PNAS:16

“When SARS, additionally a coronavirus, appeared in China and unfold globally practically 20 years in the past, Hotez was amongst researchers who started investigating a possible vaccine.

In early assessments of his candidate, he witnessed how immune cells of vaccinated animals attacked lung tissue, in a lot the identical approach that the RSV vaccine had resulted in immune cells attacking children’ lungs. ‘I assumed, ‘Oh crap,’’ he recollects, noting his preliminary worry {that a} protected vaccine could once more not be potential.”

Regardless of years of extra analysis and different growth methods, immune enhancement issues stay, and, as defined by Robert F. Kennedy, Jr. in our 2020 interview, coronavirus vaccines stay infamous for creating paradoxical immune enhancement.

Wholesome 18-12 months-Previous Who Died of COVID-19 Bought Flu Shot

NBC Information Chicago reported the dying of an 18-year-old lady from Tinley Park, Ailing., who died from COVID-19 in December 2020 simply three days after being hospitalized.17 It’s the kind of tragic story that strikes worry in thousands and thousands, however it’s necessary to do not forget that one of these dying is extraordinarily uncommon.

The COVID-19 survival rate amongst newborns to age 19 is 99.997%, in accordance with information from the U.S. Facilities for Illness Management and Prevention, cited by Dr. Reid Sheftall.18 What this heartbreaking loss ought to set off, nonetheless, is elevated investigation into why a beforehand wholesome teenager died so unexpectedly from a virus that’s hardly ever harmful in that age group.

In an interview, her mom said that she had gotten a flu shot. May this have been a think about her physique’s extreme, and finally deadly, response to the virus? It’s unattainable to know, however given the growing analysis suggesting flu vaccination could worsen viral sickness, it’s a connection that have to be thought-about.

Analysis printed within the Journal of Virology in 2011, as an illustration, discovered that seasonal flu vaccine could weaken youngsters’s immune methods and enhance their probabilities of getting sick from influenza viruses not included within the vaccine.

“[L]ong-term annual vaccination utilizing inactivated vaccines could hamper the induction of cross-reactive CD8+ T cell responses by pure infections and thus could have an effect on the induction of heterosubtypic immunity. This may occasionally render younger youngsters who haven’t beforehand been contaminated with an influenza virus extra prone to an infection with a pandemic influenza virus of a novel subtype,” the researchers famous.19

Flu Pictures May Be ‘Potential Contributors’ to Pandemic

Dr. Allan S. Cunningham, a retired pediatrician, reiterated what the info bear out — that flu vaccines must be evaluated as potential causative brokers or, at the very least, contributors to the COVID-19 pandemic. In a fast response to an article printed by The BMJ, he said:20

“A randomized placebo-controlled trial in youngsters confirmed that flu pictures elevated fivefold the chance of acute respiratory infections brought on by a bunch of noninfluenza viruses, together with coronaviruses21

Such an commentary could appear counterintuitive, however it’s potential that influenza vaccines alter our immune methods non-specifically to extend susceptibility to different infections; this has been noticed with DTP and different vaccines.22 There are different immune mechanisms which may additionally clarify the commentary.

To analyze this risk, a case-control research is so as … Influenza vaccines have turn into sacred cows in some quarters, however they shouldn’t be.”

In the meantime, within the U.S. the CDC reported that the proportion of respiratory specimens submitted for influenza testing that check constructive decreased from higher than 20% to 2.3% because the begin of the pandemic.23 In brief, flu has essentially disappeared, for causes unknown. However even whereas stating that flu instances are subsequent to nonexistent this season — they nonetheless need you to get your flu shot, “particularly this season.”24

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