How Can Such a Small Group Have so A lot Energy?

Wellcome leap

This text initially appeared on Unlimited Hangout.

The world’s richest medical analysis basis, the Wellcome Belief, has teamed up with a pair of former DARPA administrators who constructed Silicon Valley’s skunkworks to usher in an age of nightmarish surveillance, together with for infants as younger as three months outdated. Their agenda can solely advance if we enable it.

A UK nonprofit with ties to international corruption all through the COVID-19 disaster in addition to historical and current ties to the UK eugenics motion launched a worldwide health-focused DARPA equal final yr. The transfer went largely unnoticed by each mainstream and impartial media.

The Wellcome Belief, which has arguably been second solely to Invoice Gates in its potential to affect occasions through the COVID-19 disaster and vaccination marketing campaign, launched its personal international equal of the Pentagon’s secretive analysis company final yr, formally to fight the “most urgent well being challenges of our time.”

Although first conceived of in 2018, this explicit Wellcome Belief initiative was spun off from the Trust last May with $300 million in preliminary funding. It rapidly attracted two former DARPA executives, who had beforehand served within the higher echelons of Silicon Valley, to handle and plan its portfolio of tasks.

This international well being DARPA, often known as Wellcome Leap, seeks to attain “breakthrough scientific and technological options” by or earlier than 2030, with a give attention to “complicated international well being challenges.” The Wellcome Belief is open about how Wellcome Leap will apply the approaches of Silicon Valley and enterprise capital companies to the well being and life science sector.

Unsurprisingly, their three present applications are poised to develop extremely invasive tech-focused, and in some instances overtly transhumanist, medical applied sciences, together with a program completely targeted on utilizing synthetic intelligence (AI), cell sensors, and wearable brain-mapping tech for youngsters three years outdated and youthful.

This Limitless Hangout investigation explores not solely the 4 present applications of Wellcome Leap but in addition the folks behind it. The ensuing image is of an extremely sinister challenge that poses not solely a terrific risk to present society however to the way forward for humanity itself. An upcoming Limitless Hangout investigation will study the historical past of the Wellcome Belief together with its position in latest and present occasions.

Leap’s Management: Merging Man and Machine for the Navy and Silicon Valley

The ambitions of the Wellcome Leap are made clear by the lady chosen to guide it, former director of the Pentagon’s DARPA, Regina Dugan. Dugan began her career at DARPA in 1996; she led a counterterrorism job drive in 1999 earlier than leaving DARPA a few yr later.

After departing DARPA, she cofounded her personal enterprise capital agency, Dugan Ventures, after which turned particular adviser to the US Military’s vice chief of workers from 2001 to 2003, which coincided with the invasions of Afghanistan and Iraq. In 2005, she created a defense-focused tech agency referred to as RedXDefense, which contracts with the navy and particularly for DARPA.

In 2009, beneath the Obama administration, Dugan was appointed director of DARPA by Protection Secretary Robert Gates. A lot was revamped her being the primary feminine director of the company, however she is finest remembered on the company for her so-called “Particular Forces” method to innovation. Throughout her tenure, she created DARPA’s now defunct Transformational Convergence Technology Office, which targeted on social networks, artificial biology, and machine intelligence.

Lots of the themes beforehand managed by that workplace are actually overseen by DARPA’s Organic Applied sciences Workplace, which was created in 2014 and focuses on the whole lot “from programmable microbes to human-machine symbiosis.” The Organic Applied sciences Workplace, like Wellcome Leap, pursues a mixture of “health-focused” biotechnology applications and transhumanist endeavors.

Proper earlier than leaving the highest position at DARPA, Dugan greenlighted the agency’s initial investments in mRNA vaccine technology, which led to DARPA’s investments in Pfizer and Moderna shortly thereafter. The DARPA scientist who lobbied Dugan to again this system, Dan Wattendorf, now works because the director of Modern Know-how Options on the Invoice & Melinda Gates Basis.

Whereas Dugan’s efforts at DARPA are remembered fondly by these within the national-security state, and in addition by these in Silicon Valley, Dugan was investigated for conflicts of curiosity throughout her time as DARPA’s director, as her agency RedXDefense acquired hundreds of thousands in Division of Protection contracts throughout her tenure.

Although she had recused herself from any formal position on the firm whereas main DARPA, she continued to carry a major monetary stake within the firm, and a navy investigation later found she had violated ethics guidelines to a major diploma.

As a substitute of being held accountable in any approach, Dugan went on to turn out to be a high government at Google, the place she was introduced on to handle Google’s Advanced Technology and Products Group (ATAP), which it had spun out of Motorola Mobility after Google’s acquisition of that firm in 2012. Google’s ATAP was modeled after DARPA and employed different ex-DARPA officers moreover Dugan.

At Google, Dugan oversaw a number of tasks, together with what’s now the premise of Google’s “augmented actuality” enterprise, then often known as Project Tango, in addition to “smart” clothing wherein multitouch sensors had been woven into textiles. One other challenge that Dugan led concerned the usage of a “digital tattoo” to unlock smartphones. Maybe most controversially, Dugan was additionally behind the creation of a “digital authentication capsule.”

According to Dugan, when the capsule is swallowed, “your whole physique turns into your authentication token.” Dugan framed the capsule and plenty of of her different efforts at Google as working to repair “the mechanical mismatch between people and electronics” by producing expertise that merges the human physique with machines to various levels.

Whereas serving on this capability at Google, Dugan chaired a panel on the 2013 Clinton International Initiative referred to as “Sport-Changers in Know-how” and attended the 2015 Bilderberg meeting the place AI was a principal matter of debate.

In 2016, Dugan left Google for Fb the place she was chosen to be the primary head of Fb’s personal DARPA-equivalent analysis company, then often known as Constructing 8. DARPA’s ties to the origins of Fb had been mentioned in a recent Unlimited Hangout report.

Beneath Dugan, Constructing 8 invested closely in brain-machine interface expertise, which has since produced the corporate’s “neural wearable” wristbands that declare to have the ability to anticipate actions of the hand and fingers from mind alerts alone. Fb showcased prototypes of the challenge earlier this yr.

Dugan left Fb simply eighteen months after becoming a member of Constructing 8, announcing her plans “to give attention to constructing and main a brand new endeavor,” which was apparently a reference to Wellcome Leap. Dugan later said it was as if she had been coaching for her position at Wellcome Leap ever since getting into the workforce, framing it as the top of her profession.

When requested in an interview earlier this yr who the shoppers of Wellcome Leap are, Dugan gave a long-winded reply however primarily responded that the challenge serves the biotech and pharmaceutical industries, worldwide organizations such because the UN, and public-private partnerships.

Along with her position at Wellcome, Dugan can also be a member of the Council on International Relations-sponsored taskforce on US Know-how and Innovation coverage, which was shaped in 2019. Different members embrace LinkedIn’s Reid Hoffman, McKinsey Institute International Chairman James Manyika, former head of Google Eric Schmidt and President Biden’s controversial high science adviser Eric Lander.

The opposite government at Wellcome Leap, chief working officer Ken Gabriel, has a background intently tied to Dugan’s. Gabriel, like Dugan, is a former program supervisor at DARPA, the place he led the company’s microelectromechanical methods (MEMS) analysis from 1992 to 1996.

He served as deputy director of DARPA from 1995 to 1996 and have become director of the Electronics Know-how Workplace from 1996 to 1997, the place he was reportedly chargeable for about half of all federal electronics-technology investments. At DARPA, Gabriel labored intently with the FBI and the CIA.

Ken Gabriel
Ken Gabriel – COO of Wellcome Leap. Supply: Wellcome Leap

Gabriel left DARPA for Carnegie Mellon College, the place he was in control of the Workplace for Safety Applied sciences within the aftermath of September 11, 2001. That workplace was created after 9/11 particularly to assist meet the national-security wants of the federal authorities, in response to Carnegie Mellon’s announcement of this system.

Round that very same time, Gabriel turned thought to be “the architect of the MEMS trade” on account of his previous work at DARPA and his founding of the MEMS-focused semiconductor firm Akustica in 2002. He served as Akustica’s chairman and chief expertise officer till 2009, at which period he returned to work at DARPA the place he served because the company’s deputy director, working straight beneath Regina Dugan.

In 2012, Gabriel adopted Dugan to Google’s Superior Know-how and Merchandise Group, which he was really chargeable for creating. According to Gabriel, Google cofounders Larry Web page and Sergey Brin tasked Gabriel with creating “a personal sector ground-up mannequin of DARPA” out of Motorola Mobility. Regina Dugan was positioned in cost, and Gabriel once more served as her deputy.

In 2013, Dugan and Gabriel co-wrote a bit for the Harvard Business Review about how DARPA’s “Particular Forces” innovation method may revolutionize each the private and non-private sectors if extra broadly utilized.

Gabriel left Google in 2014, properly earlier than Dugan, to function the president and CEO of Charles Stark Draper Laboratories, higher often known as Draper Labs, which develops “progressive expertise options” for the national-security neighborhood, with a give attention to biomedical methods, power, and house expertise. Gabriel held that place till he abruptly resigned in 2020 to co-lead Wellcome Leap with Dugan.

Along with his position at Wellcome, Gabriel can also be a World Financial Discussion board “technology pioneer” and on the board of directors of Galvani Bioelectronics, a three way partnership of GlaxoSmithKline, which is intimately linked to the Wellcome Belief, and the Google subsidiary Verily.

Galvani focuses on the event of “bioelectronic medicines” that contain “implant-based modulation of neural alerts” in an overt push by the pharmaceutical trade and Silicon Valley to normalize transhumanist “medicines.”

The longtime chairman of the board of Galvani, on which Gabriel serves, was Moncef Slaoui, who led the US COVID-19 vaccine improvement and distribution program Operation Warp Velocity. Slaoui was relieved of his position at Galvani this previous March over well-substantiated claims of sexual harassment.

Jeremy Farrar, Pandemic Narrative Supervisor

Whereas Dugan and Gabriel ostensibly lead the outfit, Wellcome Leap is the brainchild of Jeremy Farrar and Mike Ferguson, who function its administrators. Farrar is the director of the Wellcome Belief itself, and Ferguson is deputy chair of the Belief’s board of governors.

Farrar has been director of the Wellcome Belief since 2013 and has been actively concerned in essential choice making on the highest stage globally because the starting of the COVID disaster. He’s additionally an agenda contributor to the World Financial Discussion board and cochaired the WEF’s Africa assembly in 2019.

Farrar’s Wellcome Belief can also be a WEF strategic associate and cofounded the COVID Motion Platform with the WEF. Farrar was extra lately behind the creation of Wellcome’s COVID-Zero initiative, which can also be tied to the WEF.

Farrar has framed that initiative as “a chance for firms to advance the science which is able to finally cut back enterprise disruption.” To date it has satisfied titans of finance, together with Mastercard and Citadel, to take a position hundreds of thousands in analysis and improvement at organizations favored by the Wellcome Belief.

Wellcome Trust Director Jeremy Farrar with NTI Co-Chairman Sam Nunn
Wellcome Belief Director Jeremy Farrar with NTI Co-Chairman Sam Nunn, who led the 2001 Dark Winter exercise.

A few of Wellcome’s controversial medical-research tasks in Africa, in addition to its ties to the UK eugenics motion, had been explored in a December article revealed at Unlimited Hangout.

That report additionally explores the intimate connections of Wellcome to the Oxford-AstraZeneca COVID-19 vaccine, the usage of which has now been restricted or banned in a number of nations. As talked about within the introduction, the Wellcome Belief itself is the topic of an upcoming Limitless Hangout investigation (Half 2).

Jeremy Farrar, who was born in Singapore in 1961, had beforehand been director of the Oxford University Clinical Research Unit in Ho Chi Minh City, starting in 1998. Throughout that point, he authored quite a few epidemiological analysis papers. He claimed in a 2014 Financial Times article that his choice to maneuver to Vietnam was on account of his disdain for convention halls stuffed with white males.

Southeast Asia was clearly a a lot much less regulated setting for somebody within the medical-research trade wishing to take pleasure in groundbreaking analysis. Though based mostly in Vietnam, Farrar was despatched by Oxford to varied places across the globe to check epidemics occurring in actual time.

In 2009, when swine flu was wreaking havoc in Mexico, Farrar jumped on a plane to dive proper into the motion, one thing he additionally did for subsequent international outbreaks of Ebola, MERS, and avian flu.

Over the previous yr, many questions have arisen relating to precisely how a lot energy Farrar wields over international public well being coverage. Not too long ago, the US president’s chief medical adviser, Anthony Fauci, was compelled to launch his emails and correspondence from March and April 2020 on the request of the Washington Publish.

The launched emails reveal what seems to be a high-level conspiracy by a number of the high medical authorities within the US to falsely declare that COVID-19 may solely have been of zoonotic origin, regardless of indications on the contrary. The emails had been closely redacted as such emails normally are, supposedly to guard the data of the folks concerned, however the “(b)(6)” redactions additionally defend a lot of Jeremy Farrar’s enter into these discussions.

Chris Martenson, financial researcher and post-doctorate pupil of neurotoxicology and founding father of Peak Prosperity, has had some insightful feedback on the matter, together with asking why such safety has been supplied to Farrar given that he’s the director of a “charitable belief.” Martenson went on to query why the Wellcome Belief was concerned in any respect in these high-level discussions.

One Fauci e mail, dated February 25, 2020, and despatched by Amelie Rioux of the WHO, acknowledged that Jeremy Farrar’s official position at the moment was “to behave because the board’s focus on the COVID-19 outbreak, to symbolize and advise the board on the science of the outbreak and the financing of the response.”

Farrar had previously chaired the WHO’s Scientific Advisory Council. The emails additionally present the preparation, inside a ten-day interval, of the SARS-CoV-2 “‘origins” paper, which was entitled “The Proximal Origin of SARS-CoV-2” and was accepted for publication by Nature Medication on March 17, 2020.

The paper claimed that the SARS-CoV-2 virus may solely have come from pure origins versus gain-of-function analysis, a declare as soon as held as gospel within the mainstream however which has come beneath appreciable scrutiny in latest weeks.

Shaping the presentation of an origin story for a virus of worldwide significance is one thing Farrar has been concerned with earlier than. In 2004–5, it was reported that Farrar and his Vietnamese colleague Tran Tinh Hien, the vice director on the Hospital for Tropical Illnesses, had been the primary to determine the re-emergence of the avian flu (H5N1) in people.

Farrar has recounted the origin story on many events, stating: “It was a little bit lady. She caught it from a pet duck that had died and she or he’d dug up and reburied. She survived.” In keeping with Farrar, this expertise prompted him to discovered a worldwide community along with the World Well being Group to “enhance native responses to illness outbreaks.”

An article revealed by Rockefeller College Press’s Journal of Experimental Medication in 2009 is dramatically titled, “Jeremy Farrar: When Catastrophe Strikes.” Farrar, when referring to the H5N1 origin story stated: “The WHO folks—and this isn’t a criticism—determined it was unlikely that the kid had SARS or avian influenza.

They left, however Professor Hien stayed behind to speak with the kid and her mum. The lady admitted that she had been fairly unhappy within the earlier days with the demise of her pet duck. The lady and her brother had fought over burying the duck and, due to this argument, she had gone again, dug up the duck, and reburied it—in all probability so her brother would not know the place it was buried.

With that historical past, Professor Hien phoned me at dwelling and mentioned he was nervous concerning the little one. He took some swabs from the kid’s nostril and throat and introduced them again to the hospital. That night time the laboratory ran checks on the samples, and so they had been constructive for Influenza A.”

With Farrar now having been revealed as an instrumental a part of the workforce that crafted the official story relating to the origins of SARS-CoV-2, his earlier assertions concerning the origin of previous epidemics needs to be scrutinized.

Because the director of a “charitable belief,” Jeremy Farrar is nearly fully unaccountable for his involvement in crafting controversial narratives associated to the COVID disaster. He continues to be on the forefront of the worldwide response to COVID, partly by launching the Wellcome Leap Fund for “unconventional tasks, funded at scale” as an overt try to create a worldwide and “charitable” model of DARPA.

Certainly, Farrar, in conceiving Wellcome Leap, has positioned himself to be simply as, if no more, instrumental in constructing the inspiration for the post-COVID period as he was in constructing the inspiration for the COVID disaster itself.

That is vital as Wellcome Leap CEO Regina Dugan has labeled COVID-19 this technology’s “Sputnik second” that can launch a brand new age of “well being innovation,” very like the launching of Sputnik began a worldwide technological “house age.” Wellcome Leap totally intends to guide the pack.

“Rulers” of the Gene-Sequencing Trade

In distinction to the overt DARPA, Silicon Valley, and Wellcome connections of the others, the chairman of the board of administrators of Wellcome Leap, Jay Flatley, has a distinct background. Flatley is the long-time head of Illumina, a California-based gene-sequencing {hardware} and software program large that’s believed to at present dominate the sector of genomics.

Although he stepped down from the board of Illumina in 2016, he has continued to function the chief chairman of its board of administrators. Flatley was the primary to be chosen for a management place at Wellcome Leap, and he was chargeable for suggesting Regina Dugan for the group’s chief government officer, in response to a recent interview given by Dugan.

Illumina Campus
Illumina Campus. Supply: Glassdoor

As a profile on Illumina within the enterprise journal Quick Firm notes, Illumina “operates behind the scenes, promoting {hardware} and providers to firms and analysis establishments,” amongst them 23andMe. 23andMe’s CEO, Anne Wojcicki, the sister of YouTube CEO Susan Wojcicki and the spouse of Google cofounder Sergey Brin, informed Quick Firm, “It is loopy. Illumina is just like the ruler of this entire universe and nobody is aware of that.”

The report notes that 23andMe, like most firms that provide DNA sequencing and evaluation to customers, makes use of machines produced by Illumina.

In 2016, Illumina launched an “aggressive” five-year plan to “deliver genomics out of analysis labs and into medical doctors’ workplaces.” Given the present state of issues, notably the worldwide push towards gene-focused vaccines and therapies, that plan, which concludes this yr, couldn’t have been any higher timed.

Illumina’s present CEO, Francis DeSouza, previously held key posts at Microsoft and Symantec. Additionally in 2016, Illumina’s government groups forecast a future wherein people are gene examined from delivery to grave for each well being and business functions.

Whereas most firms have struggled financially through the coronavirus pandemic, some have seen a large improve in income. Illumina has witnessed its share price double because the begin of the COVID disaster.

The corporate’s $1 billion plus in income over the past tax yr was clearly helped by the short approval of the NovaSEQ 6000 machines, which might take a look at a large number of COVID samples extra rapidly than different units. A person machine has a hefty price ticket of just about $1 million, and thus they’re largely discovered at elite facilities, private labs, and top-tier universities.

Jay Flatley
Jay Flatley, Government Chairman, Illumina, talking at World Financial Discussion board in Davos 2018. Supply: WEF

Along with his long-standing management position at Illumina, Jay Flatley can also be a “digital member” of the World Financial Discussion board in addition to the lead independent director of Zymergen, a WEF “tech pioneer” firm that’s “rethinking biology and reimagining the world.”

Flatley, who has additionally attended a number of Davos conferences, has addressed the WEF on the “promise of precision [i.e., gene-specific] medication.”

At another WEF panel meeting, Flatley, alongside UK Well being Secretary Matt Hancock, promoted the thought of creating genomic sequencing of infants at delivery the norm, claiming it had “the potential to shift the healthcare system from reactive to preventative.”

Some on the panel referred to as for the genomic sequencing of infants to finally turn out to be necessary.

Other than Flatley as a person, Illumina as an organization is a WEF partner and performs a key position in its platform relating to the way forward for well being care. A high Illumina government also serves on the WEF’s International Future Council on Biotechnology.


Wellcome Leap at present has 4 applications: Multi-Stage Psych, Delta Tissue, 1KD, and HOPE. HOPE was the primary program to be introduced by Wellcome Leap and stands for Human Organs, Physiology and Engineering. In keeping with the total program description, HOPE goals “to leverage the ability of bioengineering to advance stem cells, organoids, and entire organ methods and connections that recapitulate human physiology in vitro and restore very important capabilities in vivo.”

human organs physiology and engineering
Supply: Wellcome Leap,

HOPE consists of two main program goals. First, it seeks to “bioengineer a multiorgan platform that recreates human immunological responses with adequate constancy to double the predictive worth of a preclinical trial with respect to efficacy, toxicity and immunogenicity for therapeutic interventions.”

In different phrases, this bioengineered platform mimicking human organs could be used to check the results of pharmaceutical merchandise, together with vaccines, which may create a state of affairs wherein animal trials are changed with trials on gene-edited and farmed organs.

Although such an advance would definitely be useful within the sense of lowering usually unethical animal experimentation, trusting such a novel system to permit medical therapies to go straight to the human-testing section would additionally require trusting the establishments growing that system and its funders.

Because it stands now, the Wellcome Belief has too many ties to deprave actors within the pharmaceutical trade, having initially begun because the “philanthropic” arm of UK drug large GlaxoSmithKline, for anybody to belief what they’re producing with out precise impartial affirmation, given the histories of a few of their companions in fudging each animal and human medical trial knowledge for vaccines and different merchandise.

The second aim of HOPE is to open up the usage of machine-human hybrid organs for transplantation into human beings. That aim focuses on restoring “organ capabilities utilizing cultivated organs or organic/artificial hybrid methods” with the later aim of bioengineering a completely transplantable human organ after a number of years.

Afterward in this system description, nevertheless, the curiosity in merging the artificial and organic turns into clearer when it states: “The time is true to foster synergies between organoids, bioengineering and immunoengineering applied sciences, and advance the state-of-the-art of in vitro human biology … by constructing controllable, accessible and scalable methods.”

This system description doc additionally notes the curiosity of Wellcome in genetic-engineering approaches for the “enhancement of desired properties and insertion of traceable markers” and Wellcome’s ambition to breed the constructing blocks of the human immune system and human organ methods by way of technological means.

Transhumanist Toddlers?

The second program to be pursued by Wellcome Leap is named “The First 1000 Days: Selling Wholesome Mind Networks,” which is abbreviated as 1KD by the group. It’s arguably essentially the most unsettling program as a result of it seeks to make use of younger youngsters, particularly infants from three months to three-year-old toddlers, as its take a look at topics.

This system is being overseen by Holly Baines, who beforehand served as technique improvement lead for the Wellcome Belief earlier than becoming a member of Wellcome Leap because the 1KD program chief.

the first 1000 days
Supply: Wellcome Leap,

1KD is focused on growing “goal, scalable methods to evaluate a baby’s cognitive well being” by monitoring the mind improvement and performance of infants and toddlers, permitting practitioners to “risk-stratify youngsters” and “predict responses to interventions” in growing brains.

This system description doc notes that, up up to now in historical past, “our main window into the growing mind has been neuroimaging methods and animal fashions, which can assist determine quantitative biomarkers of [neural] community well being and characterise community variations underlying behaviours.” It then states that advances in expertise “are opening further potentialities in younger infants.”

This system description goes on to say that synthetic neural networks, a type of AI, “have demonstrated the viability of modelling community pruning course of and the acquisition of complicated behaviours in a lot the identical approach as a growing mind,” whereas enhancements in machine studying, one other subset of AI, can now be used to extract “significant alerts” from the brains of infants and younger youngsters.

These algorithms can then be used to develop “interventions” for younger youngsters deemed by different algorithms to be at risk of getting underdeveloped mind perform.

The doc goes on to notice the promise of “low-cost cell sensors, wearables and home-based methods” in “offering a brand new alternative to evaluate the affect and dependency of mind improvement on pure bodily and social interactions.”

In different phrases, this program seeks to make use of “steady visible and audio recordings within the dwelling” in addition to wearable units on youngsters to gather hundreds of thousands upon hundreds of thousands of knowledge factors. Wellcome Leap describes these wearables as “comparatively unobtrusive, scalable digital badges that gather visible, auditory and movement knowledge in addition to interactive options (equivalent to turn-taking, pacing and response occasions).”

Elsewhere within the doc there’s a name to develop “wearable sensors that assess physiological measures predictive of mind well being (e.g., electrodermal exercise, respiratory charge, and coronary heart charge) and wi-fi wearable EEG or eye-tracking expertise” to be used in infants and kids three and beneath.

Like different Wellcome Leap applications, this expertise is being developed with the intention of creating it mainstream in medical science inside the subsequent 5 to 10 years, that means that this technique—though framed as a method to monitor youngsters’s mind functioning to enhance cognitive outcomes—is a recipe for complete surveillance of infants and really younger youngsters in addition to a method for altering their mind functioning as algorithms and Leap’s programmers see match.

1DK has two principal program targets. The primary is to “develop a completely built-in mannequin and quantitive measurement instruments of community improvement within the first 1000 days [of life], adequate to foretell EF [executive function] formation earlier than a baby’s first birthday.”

Such a mannequin, the outline reads, “ought to predict contributions of diet, the microbiome and the genome” on mind formation in addition to the results of “sensimotor and social interactions [or lack thereof] on community pruning processes” and EF outcomes. The second aim makes it clear that widespread adoption of such neurological-monitoring applied sciences in younger youngsters and infants is the endgame for 1DK.

It states that this system plans to “create scalable strategies for optimising promotion, prevention, screening and therapeutic interventions to enhance EF by no less than 20% in 80% of kids earlier than age 3.”

True to the eugenicist ties of the Wellcome Belief (to be explored extra in-depth in Half 2), Wellcome Leap’s 1DK notes that “of curiosity are enhancements from underdeveloped EF to normative or from normative to well-developed EF throughout the inhabitants to ship the broadest influence.”

One of many targets of 1DK is thus not treating illness or addressing a “international well being public problem” however as an alternative experimenting on the cognitive augmentation of kids utilizing means developed by AI algorithms and invasive surveillance-based expertise.

One other unsettling side of this system is its plan to “develop an in vitro 3D mind assembloid that replicates the time formation” of a growing mind that’s akin to the fashions developed by monitoring the mind improvement of infants and kids.

Afterward, this system description calls this an “in-silico” mannequin of a kid’s mind, one thing of apparent curiosity to transhumanists who see such a improvement as a harbinger of the so-called singularity.

Past that, it seems that this in-silico and thus artificial mannequin of the mind is deliberate for use because the “mannequin” to which toddler and kids brains are formed by the “therapeutic interventions” talked about elsewhere in this system description.

It needs to be clear how sinister it’s that a company that brings collectively the worst “mad scientist” impulses of each the NGO and military-research worlds is overtly planning to conduct such experiments on the brains of infants and toddlers, viewing them as datasets and their brains as one thing to be “pruned” by machine “intelligence.”

Permitting such a program to advance unimpeded with out pushback from the general public would imply allowing a harmful agenda concentrating on society’s youngest and most weak members to probably advance to some extent the place it’s tough to cease.

A “Tissue Time Machine”

The third and second-most latest program to hitch the Wellcome Leap lineup is named Delta Tissue, abbreviated by the group as ΔT. Delta Tissue goals to create a platform that screens adjustments in human-tissue perform and interactions in actual time, ostensibly to “clarify the standing of a illness in every particular person and higher predict how that illness would progress.”

Referring to this platform as a “tissue time machine,” Wellcome Leap sees Delta Tissue as having the ability to predict the onset of illness earlier than it happens whereas additionally permitting for medical interventions that “are focused to the person.”

delta tissue
Supply: Wellcome Leap,

Nicely earlier than the COVID period, precision medication or medication “focused or tailor-made to the person” has been a code phrase for therapies based mostly on sufferers’ genetic knowledge and/or for therapies that alter nucleic acid (e.g., DNA and RNA) perform itself. As an example, the US authorities defines “precision medicine” as “an rising method for illness remedy and prevention that takes under consideration particular person variability in genes, setting, and way of life for every particular person.”

Equally, a 2018 paper revealed in Know-how notes that, in oncology, “precision and customized medication … fosters the event of specialised therapies for every particular subtype of most cancers, based mostly on the measurement and manipulation of key affected person genetic and omic knowledge (transcriptomics, metabolomics, proteomics, and many others.).”

Previous to COVID-19 and the vaccine roll outs, the mRNA vaccine expertise utilized by the DARPA-funded firms Moderna and Pfizer had been marketed as being precision medicine treatments and had been largely known as “gene therapies” in media studies.

They had been additionally promoted closely as a revolutionary methodology of treating most cancers, making it unsurprising that the Delta Tissue program at Wellcome Leap would use an identical justification to develop a program that goals to supply tailor-made gene therapies to folks earlier than the onset of a illness.

This Delta Tissue platform works to mix “the newest cell and tissue profiling applied sciences with latest advances in machine studying,” that’s, AI.

Given Wellcome Leap’s connections to the US navy, it’s price noting that the Pentagon and Google, each former employers of Wellcome Leap CEO Regina Dugan and COO Ken Gabriel, have been working collectively since final September on utilizing AI to foretell illness in people, first specializing in most cancers earlier than increasing to COVID-19 and each illness in between.

The Delta Tissue program seems to have associated ambitions, as its program description makes clear that this system in the end goals to make use of its platform for a bunch of cancers and infectious ailments.

The last word aim of this Wellcome Leap program is “to eradicate the stubbornly difficult ailments that trigger a lot struggling around the globe.” It plans to do that by way of AI algorithms, nevertheless, that are by no means one hundred pc correct of their predictive potential, and with gene-editing therapies, practically all of that are novel and haven’t been properly examined.

That latter level is necessary on condition that one of many principal strategies for gene-editing in people, CRISPR, has been present in quite a few research to trigger appreciable harm to the DNA, harm that’s largely irreparable (see here, here and here).

It appears believable that an individual positioned on such a hi-tech medical remedy path will proceed to wish a unending sequence of gene-editing therapies and maybe different invasive hi-tech therapies to mitigate and handle the results of clumsy gene splicing.

Whole Surveillance to Deal with “Melancholy”

Wellcome Leap’s most up-to-date program, launched simply this week, is named “Multi-Channel Psych: Revealing Mechanisms of Anhedonia” and is formally targeted on creating “complicated, organic” therapies for despair.

multi channel psych
Supply: Wellcome Leap,

These behind Wellcome Leap frame the problem they goal to deal with with this program as follows:

“We perceive that synaptic connections function the foreign money of neural communication, and that strengthening or weakening these connections can facilitate studying new behavioral methods and methods of trying on the world.

Via research in each animal fashions and people, we have now found that emotional states are encoded in complicated neural community exercise patterns, and that straight altering these patterns by way of mind stimulation can shift temper. We additionally know that disruption of those delicately balanced networks can result in neuropsychiatric sickness.” (emphasis added)

They add that “biologically based mostly therapies” for despair “usually are not being matched to the biology of the human beings they’re being utilized in,” and, thus, therapies for despair have to be tailor-made “to the particular biology” of particular person sufferers. They clearly state that what must be addressed so as to make such private modifications to remedy is to realize “quick access to the organic substrate of despair—i.e. the mind.”

Wellcome Leap’s program description notes that this effort will focus particularly on anhedonia, which it defines as “an impairment within the effort-based reward system” and as a “key symptom of despair and different neuropsychiatric sicknesses.” Notably, within the tremendous print of the doc, Wellcome Leap states:

“Whereas there are a lot of definitions of anhedonia, we’re much less within the investigation of decreased consummatory pleasure, the final expertise of delight, or the lack to expertise pleasure. Fairly, as per the outline above, we are going to prioritize investigations of anhedonia because it pertains to impairments within the effort-based reward system—e.g. decreased motivation to finish duties and decreased capability to use effort to attain a aim.”

In different phrases, Wellcome Leap is barely curious about treating points of despair that intrude with a person’s potential to work, not in bettering a person’s high quality or enjoyment of life.

Leap notes, in discussing its targets, that it seeks to develop fashions for a way sufferers reply to therapies that embrace “novel or current conduct modification, psychotherapy, remedy, and neurostimulation choices” whereas additionally capturing a person’s “genome, phenome [the sum of an individual’s phenotypic traits], [neural] community connectivity, metabolome [the sum of an individual’s metabolic traits], microbiome, reward processing plasticity ranges,” amongst others.

It in the end goals to foretell the connection between a person’s genome to how “reward processing” capabilities within the mind. It implies that the info used to create this mannequin ought to contain the usage of wearables, stating that researchers “ought to search to leverage excessive frequency patient-worn or in-home measurements along with these obtained within the clinic, hospital or laboratory.”

One of many principal analysis areas included in this system appears to “develop new scalable measurement instruments for dependable and high-density quantification of temper (each subjectively reported and objectively quantified by way of biometrics equivalent to voice, facial features, and many others.), sleep, motion, reward system functioning, effort/motivation/power ranges, social interplay, caloric consumption, and HPA axis output in real-world conditions.”

The HPA (hypothalamic-pituitary-adrenal) axis is talked about all through the doc, and that is vital as it’s each a detrimental and constructive suggestions system regulating the mechanisms of stress reactions, immunity, and in addition fertility within the human physique.

The latter is very necessary given the Wellcome Belief’s ties to the UK eugenics motion. It is usually price noting that some commercially accessible wearables, equivalent to Amazon’s Halo, already quantify temper, sleep, and motion.

This system’s authors go even additional than the above when it comes to what they want to monitor in actual time, stating, “We particularly encourage the event of non-invasive expertise to straight interrogate human mind state.” Examples embrace “a non-invasive spinal faucet equal,” “behavioral or biomarker probes of neural plasticity,” and “single-session neural monitoring capabilities that outline a treatment-predictive mind state.”

In different phrases, this Wellcome Leap program and its authors search to develop “non-invasive” and, seemingly, wearable expertise able to monitoring a person’s temper, facial expressions, social interactions, effort and motivation, and probably even ideas so as to “straight interrogate human mind state.”

To suppose that such a tool would keep solely within the realm of analysis is naive, particularly on condition that WEF luminaries have openly spoken at Davos meetings about how governments plan to make use of such expertise broadly on their populations as a method of pre-emptively concentrating on would-be dissent and ushering in an period of “digital dictatorships.”

The give attention to treating solely the points of despair that intrude with an individual’s work additional means that such expertise, as soon as developed, could be used to make sure “excellent employee” conduct in industries the place human staff are quickly being changed with AI and machines, that means the rulers will be extra selective about which individuals proceed to be employed and which don’t.

Like different Wellcome Leap applications, if accomplished, the fruits of the Multi-Channel Psych program will seemingly be used to make sure a inhabitants of docile automatons whose actions and ideas are closely surveilled and monitored.

The Final Leap for an Outdated Agenda

Wellcome Leap isn’t any small endeavor, and its administrators have the funding, affect, and connections to make their goals actuality. The group’s management contains the important thing drive behind Silicon Valley’s push to commercialize transhumanist tech (Regina Dugan), the “architect” of the MEMS trade (Ken Gabriel), and the “ruler” of the burgeoning genetic-sequencing trade (Jay Flatley).

It additionally advantages from the funding of the world’s largest medical-research basis, the Wellcome Belief, which can also be one of many main forces in shaping genetics and biotechnology analysis in addition to well being coverage globally.

A 1994 Sunday Times investigation into the Belief famous that “by way of [Wellcome Trust] grants and sponsorships, authorities companies, universities, hospitals and scientists are influenced all around the world. The belief distributes extra money to establishments than even the British authorities’s Medical Analysis Council.” It then notes:

“In workplaces on the constructing’s first flooring, choices are reached that have an effect on lives and well being on scales comparable with minor wars. Within the convention room, excessive above the road, and within the assembly corridor, within the basement, rulings in biotechnology and genetics are handed down that can assist form the human race.”

Little has modified relating to the Belief’s affect since that article was revealed. If something, its affect on analysis paths and choices that can “form the human race” has solely grown. Its ex-DARPA officers, who’ve spent their careers advancing transhumanist expertise in each the private and non-private sectors, have overlapping targets with these off Wellcome Leap.

Dugan’s and Gabriel’s business tasks in Silicon Valley reveal that Leap is led by those that have lengthy sought to advance the identical expertise for revenue and for surveillance. This drastically weakens Wellcome Leap’s declare to now be pursuing such applied sciences to solely enhance “international well being.”

type from your brain
Regina Dugan’s Keynote at Fb F8 2017. Supply: YouTube

Certainly, as this report has proven, most of those applied sciences would usher in a deeply disturbing period of mass surveillance over each the exterior and inner actions of human beings, together with younger youngsters and infants, whereas additionally creating a brand new period of drugs based mostly largely on gene-editing therapies, the dangers of that are appreciable and in addition persistently downplayed by its promoters.

When one understands the intimate bond that has lengthy existed between eugenics and transhumanism, Wellcome Leap and its ambitions make excellent sense. In a latest article written by John Klyczek for Unlimited Hangout, it was famous that the primary director basic of UNESCO and former president of the UK Eugenics Society was Julian Huxley, who coined the time period “transhumanism” in his 1957 e-book New Bottles for New Wine.

As Klyczek wrote, Huxley argued that “the eugenic targets of biologically engineering human evolution needs to be refined by way of transhumanist applied sciences, which mix the eugenic strategies of genetic engineering with neurotech that merges people and machines into a brand new organism.”

Earlier, in 1946, Huxley noted in his vision for UNESCO that it was important that “the eugenic drawback is examined with the best care and that the general public thoughts is knowledgeable of the problems at stake in order that a lot that’s now unthinkable might no less than turn out to be thinkable,” an astounding assertion to make so quickly after the tip of World Conflict II.

Thanks largely to the Wellcome Belief and its affect on each coverage and medical analysis over the course of a number of a long time, Huxley’s dream of rehabilitating eugenics-infused science within the submit–World Conflict II period may quickly turn out to be actuality. Unsurprisingly, the Wellcome Belief hosts the archive of the previously Huxley-led Eugenics Society and still boasts close ties to its successor group, the Galton Institute.

The over-riding query is: Will we enable ourselves to proceed to be manipulated into permitting transhumanism and eugenics to be overtly pursued and normalized, together with by way of initiatives like these of Wellcome Leap that search to make use of infants and toddlers as take a look at topics to advance their nightmarish imaginative and prescient for humanity?

If well-crafted promoting slogans and media campaigns portray visions of utopia equivalent to “a world with out illness” are all that’s wanted to persuade us to surrender our future and our kids’s future to navy operatives, company executives, and eugenicists, then there may be little left of our humanity to give up.

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